Easy visualization of the read coverage using the CoverageView package
نویسنده
چکیده
This package is used for the visualization of the read coverage. It allows the user to calculate the read coverage and to generate different types of coverage displays. It is designed to be used with the files produced after the alignment of the reads generated in different types of next-generation sequencing experiments against the reference sequences (i.e. genome or transcriptome). CoverageView produces a visual representation of the genomic regions that are read-enriched and therefore have greater coverage depth; this is specially useful for ChIP-seq or genome-wide nucleosome positioning experiments, where the enrichment along a certain genomic region can be visualized in a single sample or across different samples. Additionally, CoverageView can also be used in RNA-seq experiments in order to compare how the coverage is distributed along the transcriptome.
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